Two persons were seriously injured Saturday night in a one-vehicle crash near Simmons, the Missouri State Highway Patrol said.
Tpr. Travis Brown said a southbound 2014 Chevrolet Cruze ran off the right side of the roadway, struck an embankment and overturned.
The driver, Margaret K. Delisle, 49, and a passenger, William A. Delisle, 45, both of Boss, were flown to Cox South in Springfield.
Brown said the driver was wearing a seatbelt and her passenger was not. The vehicle was totaled.
Assisting at the scene were Tpr. Marty Wiseman, the Cabool Fire Department and Houston Rural Fire Department.