A 24-year-old Mountain Grove woman was seriously injured early Sunday in a Route 95 accident north of Manes.
Cpl. Travis Brown said a northbound 2003 Ford F-150 truck skidded off the roadway, rotated and overturned at about 2:10 a.m.
The driver, who was not wearing a seat belt, was taken by ambulance to Cox South in Springfield.
The vehicle was totaled.